Is Poughkeepsie "upstate"? I think of Upstate as being, like, Albany and west and north of there.
To the extent that "Upstate" can be defined in a technical, non-anecdotal manner, it would include the counties that are not part of the New York CMSA. North of the city, the counties within the CMSA (and therefore not Upstate) are Westchester, Rockland, Orange, Putnam and Dutchess. Poughkeepsie is of course part of Dutchess County and therefore is not Upstate.